PRIME Consortium

Unleashing the Power of Collaboration in Infectious Disease Innovation

About us

We have assembled an international team of infectious disease experts, microbiologists, database experts, and analytical multi-omics experts to develop a new approach to treating infections.

Leadership

  • Ian Lewis, Ph.D.

    University of Calgary

    Principal Investigator of the ResistanceDB and Calgary BSI Cohort project at the University of Calgary and ACAD.

  • Ashlee M. Earl, Ph.D.

    Broad Institute

    Director of Bacterial Genomics at the Broad Institute of MIT and Harvard, working with infectious diseases and the microbiome.

  • Hallgrimur Benediktsson, MD FRCPC

    University of Calgary

    Professor at the University of Calgary's Department of Community Health Sciences, providing valuable clinical advisory insights.

  • Yonatan H. Grad, MD Ph.D.

    Harvard T.H. Chan School of Public Health

    Professor at Harvard's Department of Immunology and Infectious Diseases with a focus on the genetic underpinnings of infections’ epidemiology.

  • Daniel B. Gregson, MD FRCPC

    University of Calgary

    Professor at the University of Calgary departments of Pathology and Laboratory Medicine with a focus on epidemiology and diagnosis of blood stream infections.

  • Bruce J. Walker, B. Sc. Physics

    Broad Institute

    Principal Genomics Data Analyst at the Broad Institute's Infectious Disease & Microbiome Program, specializes in high-performance computing-driven genomics data analysis.

  • M. Ethan MacDonald, Ph.D.

    University of Calgary

    Assistant Professor at the University of Calgary's Department of Biomedical Engineering, focusing on machine learning applications within the biomedical field.

  • Sergei Y. Noskov, Ph.D. (in memoriam)

    University of Calgary

    Professor, in memoriam, at the Univemsity of Calgary made significant contributions in the field of machine learning, data integration and data science.

Project Management and Team Leads

  • Troy Feener, M.Sc.

    Project Manager

  • Annegret Ulke-Lemée, Ph.D.

    Project Coordinator and Team Lead

    Proteomics

  • Ryan Groves, M.Sc.

    Team Lead

    Metabolomics​

  • Thomas Rydzak, Ph.D.

    Team Lead

    Microbiology​

  • Sören Wacker, Ph.D.

    Team Lead

    Data Analysis

Clinical Network

  • Gregory Tyrrell, Ph.D.

    Medical microbiologist and clinical department section chief at Alberta Precision Laboratories with a focus on Streptococci and tuberculosis.

  • Aru Narendran, MD, Ph.D.

    Professor of pediatric oncology at the University of Calgary working with acute lymphoblastic leukemia and linked bacterial infections.

  • Dylan R. Pillai, MD, Ph.D.

    Professor of Pathology and Laboratory Medicine at the University of Calgary, focussing on infectious disease and point of care testing.

  • Marcello Tonelli, MD​

    Associate Vice President of Health Research and Professor at the University of Calgary focusing on chronic kidney disease and associated infections as well as health policy.

  • Tanis Dingle, Ph.D. FCCM

    Clinical microbiologist at Alberta Precision Laboratories with a focus on epidemiology and assessing microbial resistance.

  • Michael Parkins, MD, M.Sc.

    Assistant Professor in the microbial research group of the University of Calgary, working with cystic fibrosis chronic lung infection and the role of P. aeruginosa.

  • Otto G. Vanderkooi, MD​, FRCPC.

    Director of the Pediatric Infectious Disease program at the University of Calgary, researching microbiology and infectious diseases in children.

  • John Conly, MD, FRCPC, Ph.D.

    Professor in microbiology, immunology and infectious diseases at the University of Calgary with a focus on antimicrobial resistance and stewardship.

Advisory Committee

  • Edward L. Huttlin, Ph.D.

    Instructor at Harvard Medical School and protein mass spectrometry expert for the BioPlex Interactome Project.

  • Joe Harrison, Ph.D.

    Canada Research Chair at the University of Calgary with a focus on micobiology and biofilms.

  • Diego Nobrega, Ph.D.

    Expert in veterinary epidemiology and microbiology at the University of Calgary working on surveillance of infectious diseases in animals.

  • William Hsiao, Ph.D.

    Directs the Public Health Bioinformatics Group at Simon Fraser University with a focus on genomics and disease control.

Team - Laboratory​

  • Morgan Hepburn is a Postdoctoral Fellow in Mass Spectrometry, specializing in Proteomics LC-MSMS.

  • Gopal Ramamourthy is a Technician in Microbiology, focusing on BSI isolates and DNA purification.

  • Nadia Monych (Past) is a Technician in Microbiology at Calgary Laboratory Services, contributing to BSI isolates.

  • Jenna Poelzer (Past) is a Technician in Microbiology, previously at the University of Calgary, involved in BSI isolates and 'Omics sample processing.

  • Yeganeh Khaniani (Past) is a Technician in Mass Spectrometry, involved in Omics sample preparation.

  • Aja List is a Principal Investigator and leader in Genomics, specializing in DNA sequencing and Clinical Laboratory Process Development Associate II.

  • Jason Lam is a Principal Investigator in Genomics, focusing on DNA sequencing and Clinical Laboratory Process Development Associate II.

  • Lindsey Paul is involved in Genomics as a Supervisor in Clinical Laboratory DNA sequencing, focusing on project management and administration.

  • Nick Fitzgerald is Principal Investigator in Genomics, role specifics undisclosed but likely contributing to leadership in genomics research.

  • Nithya Swaminathan is a Project Coordinator in Genomics, specializing in project management and administration.

  • Sean English is an Operations Manager in Genomics, specializing in project management and administration.

  • Jimmy Harold is a Technician in Genomics, specifically involved in DNA sequencing and Clinical Laboratory Process Development Associate II.

  • Matthew Rogers is a Technician in Genomics, specializing in DNA sequencing and Clinical Laboratory Process Development Associate II.

  • Owen Conroy is a Technician in Genomics, particularly focused on DNA sequencing and Clinical Laboratory Process Development Associate II.

Team - Data analysis

  • Alikhan Mansuri (Past) contributed to AHS and APL data at the University of Calgary, focusing on epidemiology in the CBSIC as a graduate student.​

  • Andriy Plakhotnyk is currently involved in ML and data integration at the University of Calgary's ACAD, working on Silent Polyclonal Bloodstream Infections as a graduate student.​

  • Anika Westlund presently works on AHS and APL data at the University of Calgary, specifically focusing on bacteremia patient outcomes from the Calgary BSI Cohort & metabolomics of Treponema Pallidum as a graduate student.​

  • Colin MacKenzie is currently engaged in Microbiology at the University of Calgary, studying traits modulating antimicrobial resistance in Staphylococcus aureus as a graduate student.​

  • Luis Ponce Ponce Alvarez contributes to Mass Spectrometry at the University of Calgary's ACAD, involved in modeling Small Colony Variants as a graduate student.​

  • Mario E. Valdés-Tresanco works in Mass Spectrometry at the University of Calgary, focusing on the Multiomics atlas of Calgary BSI Cohort as a graduate student.​

  • Maryam Mapar delves into Microbiology at the University of Calgary, conducting a systematic multi-omics survey of Staphylococcus aureus small colony variants as a graduate student.​

  • Racheal Apata is involved in ML and data integration at the University of Calgary, working on WGS-based identification of genetic factors conferring antimicrobial resistance in gram-positive bloodstream pathogens as a graduate student.​

  • Rory Gilliland explores ML and data integration at the University of Calgary, specifically focusing on identifying bloodstream infection clinical outcome biomarkers using machine learning as a graduate student.​

  • Madeline Kline is involved in Genomics at the University of Calgary as a graduate student, specific project details weren't provided.​

  • Tatum Mortimer operates in Genomics (previously postdoctoral fellow at Harvard, now associate professor at the University of Georgia), focusing on genomic epidemiology and the evolution of antimicrobial resistance in bacteria.​

  • Thi Mui Pham is a postdoctoral fellow and specializes in ML and data integration at Harvard, focusing on genomic epidemiology and evolution of antimicrobial resistance in bacterial pathogens as a Postdoctoral fellow.

  • Josh T. Smith operates as postdoctoral fellow in Genomics at Harvard's Infectious Disease & Microbiome Program as a Postdoctoral fellow, focusing on population genomics of bacterial pathogens in different contexts.​

  • Rauf Salamzade (Past) contributed to Genomics at The Broad Institute's Infectious Disease & Microbiome Program as a Research Techinician, analyzing and annotating microbial sequencing data.